uWSGI, send_file and Python 3.5

I have a Flask app that returns an in-memory bytes buffer (io.Bytesio) using Flask send_file function.

The app is deployed using uWSGI behind Nginx. This was working fine with Python 3.4.

When I updated Python to 3.5, I got the following exception when trying to download a file:

io.UnsupportedOperation: fileno

During handling of the above exception, another exception occurred:

Traceback (most recent call last):
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask/app.py", line 1817, in wsgi_app
    response = self.full_dispatch_request()
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask/app.py", line 1477, in full_dispatch_request
    rv = self.handle_user_exception(e)
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask/app.py", line 1381, in handle_user_exception
    reraise(exc_type, exc_value, tb)
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask/_compat.py", line 33, in reraise
    raise value
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask/app.py", line 1475, in full_dispatch_request
    rv = self.dispatch_request()
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask/app.py", line 1461, in dispatch_request
    return self.view_functions[rule.endpoint](**req.view_args)
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask_login.py", line 758, in decorated_view
    return func(*args, **kwargs)
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask_security/decorators.py", line 194, in decorated_view
    return fn(*args, **kwargs)
  File "/webapps/bowser/bowser/app/bext/views.py", line 116, in download
    as_attachment=True)
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/flask/helpers.py", line 523, in send_file
    data = wrap_file(request.environ, file)
  File "/webapps/bowser/miniconda3/envs/bowser/lib/python3.5/site-packages/werkzeug/wsgi.py", line 726, in wrap_file
    return environ.get('wsgi.file_wrapper', FileWrapper)(file, buffer_size)
SystemError: <built-in function uwsgi_sendfile> returned a result with an error set

I quickly found the following post with the same exception, but no answer... A little more googling brought me to this github issue: In python3, uwsgi fails to respond a stream from BytesIO object

As described, you should run uwsgi with the --wsgi-disable-file-wrapper flag to avoid this problem. As with all command line options, you can add the following entry in your uwsgi.ini file:

wsgi-disable-file-wrapper = true

Note that uWSGI 2.0.12 is required.

When searching in uWSGI documentation, I only found one match in uWSGI 2.0.12 release notes.

A problem/option that should be better documented. Probably a pull request to open :-)

UPDATE (2016-07-13): pull request merged